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Waterfall plots of best change in the target lesion size from baseline of BPI-9016M treated patients. The dashed lines at 20% and -30% indicate the thresholds for PD and PR, respectively. Seven patients (two patients in the 450 mg QD cohort, four patients in the 600 mg QD cohort and one patient in the 400 mg BID cohort) were not evaluable
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