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UBXN7 overexpression impairs SKIL degradation in response to TGF-β. Nuclear extracts from U2OS UBXN7-KO clone #1 cells transfected with HA-tagged empty vector (-), UBXN7-WT, UBXN7-∆UAS, or UBXN7-UAS and treated or not for 1 h with TGF-β before extraction were analyzed by western blotting. Quantification and statistics as in a except that values were normalized to the empty vector condition.

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