Velocity data for experiments shown in A . In control conditions (0 μM AS1), larval zebrafish locomote at much greater velocities in the 37.5 °C zone than in the 28.5 °C zone. Interestingly, as the concentration of AS1 increases, this velocity difference switches—velocity increases in the 28.5 °C portion but decreases in the 37.5 °C portion. At an intermediate concentration, there is no difference between velocities at 28.5 and 37.5 °C. * denotes significant differences in swimming velocities between the 28.5 and 37.5 °C zones for the same group of fish, + denotes significant difference from the 0 μM AS1 37.5 °C swimming velocity, and # denotes significant difference from the 0 μM AS1 28.5 °C swimming velocity.