Scatter Plot from Scientific Research

Quantile-quantile plots of p -values from different global mediation tests in the simulation study for the continuous outcome. The observed p -values were compared to the expected quantiles generated by the uniform null distribution. The |S_alpha| and |S_beta| denote the number of treatment-associated OTUs and outcome-associated OTUs, respectively. Different combinations of ( |S_alpha| , |S_beta| ) represent different mixtures of mediation nulls H_{00} , H_{10} , and H_{01}

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