Superposition of TcpA and FtsK structures with a close up view around key DNA-binding residues identified in FtsK depicted as sticks. FtsK is colored in light cyan and TcpA in magenta (following the initial color scheme). Residues K406, K384, and K350 in TcpA are colored in dark gray and are not strictly conserved in FtsK. These residues may play a role in TcpA/DNA interactions. A sequence alignment of this region is presented below. Conserved residues involved in DNA binding are colored in red, additional residues playing a role in DNA binding by structural homology are in bold, and the RAAG motif is underlined.
