Bar Plot from Scientific Research

Loss of SF3B1 5' UTR m6A88 delays leukemogenesis in vivo. Leukemia-free survival of sub-lethally irradiated NSG mice translated with 500.000 MOLM-13 cells harboring SF3B1 5' UTR WT and A88GMUT, respectively, n = 10 per group. p = 0.0282 (Mantel-Cox test). Graphs show decreased leukemic burden with lower MOLM-13-derived human CD45 chimerism in the A88GMUTgroup.***p < 0.001,*p < 0.05 (t test).

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