Protein Structure from Scientific Research

Pore depiction of dTRPA1-A in state-1 and state-2. A ribbon diagram is shown for the pore region from diagonally opposed subunits. Side chains of the constricting sites are shown as sticks. The upper gate is formed by residues L980, G981 and E982, and the lower gate is formed by I1024 and V1028. The ion conduction pore, calculated using HOLE2 57 , is shown as magenta or orange mesh for state-1 or state-2, respectively.

DOI