Bar Plot from Scientific Research

Unprocessed urine samples collected from tumour-bearing mice injected with DNA-encoded cMET or GFP nanobody, and healthy control mice injected with DNA-encoded cMET nanobody were applied in the Cas12a trans -cleavage assay. Initial reaction velocities ( V 0 ) were calculated and normalized to that of healthy control mice. n = 5 for control groups, n = 7 mice for DNA-encoded cMET nanobody injected group; mean ± s.e.m.; one-way analysis of variance with Tukey’s multiple-comparison test, * P = 0.028 for the normal versus cMET-Nb-DNA comparison, * P = 0.0221 for the cMET-Nb-DNA versus GFP-Nb-DNA comparison; NS, not significant where P = 0.9902 for the normal versus GFP-Nb-DNA comparison.

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