Box Plot from Scientific Research

Baseline firing rate (Hz) of POMC neurons recorded from chow-fed, DIO, DIO-VEH, and DIO-RAP mice (left to right). Firing rate is decreased in DIO (n= 155;p= 0.007) and DIO-VEH (n= 36;p= 0.003) compared with chow-fed mice (n= 51). Rapamycin (n= 28) increased the firing rate compared with DIO (n= 155,p< 0.0001) and DIO-VEH (n= 36,p= 0.0004, all Mann-Whitney tests). Error bars represent mean ± SEM.

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