The numbers of PB CD34 + cells μl –1 in each cohort are presented by mobilization day with standard box and whisker plots, where the measure of center is the median value for PB CD34 + cells μl –1 with the exact median value of CD34 + cells μl –1 noted below the x axis by day and cohort; the box represents the interquartile range and lines represent the minimum/maximum (±1.5 × interquartile range). Each patient contributed a single biologically independent sample examined over one independent experiment per sample/patient. Total sample counts associated with motixafortide + G-CSF were: day 0 ( n = 80), day 4 ( n = 80), day 5 ( n = 80), day 6 ( n = 11), day 7 ( n = 6) and day 8 ( n = 0). Total sample counts associated with placebo + G-CSF were: day 0 ( n = 39), day 4 ( n = 40), day 5 ( n = 39), day 6 ( n = 32), day 7 ( n = 27) and day 8 ( n = 17).