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Genetic correlation using LD-score regression of extensive PVS burden with putative risk factors; two-sided exact P values are provided for nominally significant results (* P < 0.05) and significant results after multiple-testing correction (** P < 7.9 x 10 -4, correcting for 21 independent phenotypes and the three PVS locations); full results are provided in Supplementary Table 9. Larger colored squares correspond to more significant P values and the colors represent the direction of the genetic correlation (positive in red, negative in blue).
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