Venn diagrams showing the overlap between the number of ChIPseq peaks identified for the indicated histone acetylation marks. The box plots below each Venn diagram show the ChIP signal intensity of the overlapping and nonoverlapping peaks. One H2BNTac peak can overlap with more than one H3K27ac peak or vice versa, which leads to slight differences in the total number of H3K27ac peak counts in the different Venn diagrams. The box plots display the median, upper and lower quartiles; the whiskers show the 1.5x interquartile range (IQR). Number of ChIPseq biological replicates: H2BK5ac D5H1S (n = 4); H3K27ac (n = 3); H2BK12ac (n = 2); H2BK16ac (n = 2); H2BK20ac EPR859 (n = 2); H2BK20ac D709W (n = 1) and H3K9ac (n = 1). Two-sided MannWhitney U-test, adjusted for multiple comparisons with the BenjaminiHochberg method; **P < 1 x 10-10, ***P < 1 x 10-50.
