UMAP from Scientific Research

Top leftgene expression UMAP of all T cells from adult human tissues in ref. 5 , colored by low-level cell type annotations. Each point represents a cell. Top middleVDJ usage frequency per celltype_donor pseudobulk is computed for each gene and used as input of the VDJ feature space. Top rightUMAP of the pseudobulk VDJ feature space of the same cells. Each point represents a cell pseudobulk. Bottom paneltop two differentially expressed TCR genes in CD4 + T cells, CD8 + T cells and MAIT cells.

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