Volcano plots indicating the enrichment of HOCOMOCO v.12 30 transcription factor families in the top 1,000 versus bottom 1,000 promoters ( f ) and potential enhancers ( g ), as ranked by MPRA activity. Enrichment (measured as an odds ratio) and BenjaminiHochberg corrected q values computed using Fisher’s exact test. Significant families above the P value acceptance threshold (dashed horizontal line) are labelled with a representative transcription factor family member with the general transcription factor family in parentheses.
