Bar Plot from Scientific Research

Open access visualization of Bar Plot, Genome browser visualization, MRE11 enrichment, Off-target site, Liver
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Genome browser visualization of MRE11 enrichment at another off-target site ('OFF-target B') with two mismatches each ('2 mm'), in the liver of mice transduced with adenovirus expressing Cas9 targeting PCSK9 . Mice were dosed twice a day (b.i.d.) with either 25 mg kg −1 Ku-60648 ('Ku-60648'; red) or with vehicle ('no drug'; blue).

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