Protein Structure from Scientific Research

Essential motions of the apo30 trajectories obtained by projecting each trajectory onto the first the principal component. The overlay of 100 structures (one every 10 ns) reproduces the motion described by the principal component over 1 us time of each trajectory. The essential dynamics differ: apo30 and holo30 describe two very different motions, the first being the characteristic hinge motion, which changes into a twist of one domain relative to the other.

DOI