Landscape Plot of genes, pathways, and biological processes most associated with the comparison of tumors versus adjacent normal samples. For each gene/pathway/biological process the average log2 fold change is plotted (x-axis) against the –log10 adjusted p-value (y-axis). Entities to the right of the vertical line (x=1) are more highly expressed in tumors compared to normal samples, while entities to the left are more highly expressed in normal samples relative to tumors. The horizontal line denotes an adjusted p-value of 0.05. Thus, entities above the horizontal line are considered significantly different between normal and tumor samples. Colors indicate general categories of entities. Genes are indicated in purple, pathways are in orange, and biological processes are in green.