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Average minimum standard error of the case parameter estimate. The standard error of the parameter estimates was estimated under each of the experimental scenarios (Table 1 ) across all 10,000 gene expression features. We estimated the average minimum standard error across all of the 1000 simulation iterations. The average minimum standard error was estimated for beta_1 (panel A, case vs control parameter that was set at 0 to represent the null hypothesis). Opt = optimal allocation strategy, R = simple randomization strategy, SR = stratified randomization strategy

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