Distribution of key functional gene clusters and genes among different lineages. Five categories of genes are shown in different colors, from left to right: biofilm formation (blue), acid resistance (turquoise), metabolism (gray), oxidative stress (green), and CRISPR-Cas and phage (purple). The function of the genes are described as follows: bfrKR , two-component regulatory system; cemKR , two-component regulatory system; asp2 , accessory Sec system protein Asp2; secA , protein translocase subunit SecA2; Lr70894 , secA2 operon component; lev , levansucrase; Lr70134 , Lr70131 , EDX43652 , EDX42265 , large surface proteins (Lsp) containing LPXTG cell wall anchoring motif; gadB , glutamate decarboxylase; gls1 , gls2 , gls3 , the 3 glutaminases; ure , urease gene cluster for urea metabolism; pdu and cbi , part of the pdu - cbi-cob-hem gene cluster that mediates 1,2-propanediol and glycerol utilization, and cobalamin biosynthesis; manA , mannose-6-phosphate isomerase; ERG8 , phosphomevalonate kinase; glpT , glycerol-3-phosphate transporter; PAD , phenolic acid decarboxylase; frc , formyl-coenzyme A transferase; rib , gene cluster for riboflavin biosynthesis; cit , citrate lyase cluster; yvyI , mannose-6-phosphate isomerase YvyI; SDR , short-chain dehydrogenases/reductases; thrBC , threonine biosynthetic cluster; cpnA , cyclopentanol dehydrogenase; rtpR , adenosylcobalamin-dependent ribonucleoside-triphosphate reductase; moaA / moaAC / moaDE / mogA / mobAB , genes for molybdenum cofactor (Moco) biosynthesis; nreB , oxygen sensor histidine kinase NreB; pnbA , nitroreductase-like family protein; tpx , redoxin domain protein; HMA , heavy metal translocating P-type ATPase; cad , cadmium resistance transporter; cas1 , CRISPR-Cas system; gp36 , phage phi-C31 major capsid gp36-like protein
