Workflow from Scientific Research

Open access visualization of Workflow, Illustration, Antiretroviral Therapy, IL-10 Mice, Growth Changes
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Antiretroviral therapy does not impact on growth changes in IL-10 -/- mice. A SvEv WT and IL-10 -/- mice commenced intervention aged 4 weeks with control (placebo) or cART for 12 weeks 1 week with daily nucleoside reverse transcriptase inhibitors (1 mg emtricitabine and 1.5 mg tenofovir disoproxil fumarate) and protease inhibitors (4 mg lopinavir boosted with 1 mg ritonavir) in drinking water. Body weight was continuously measured. Interventions occurred at 12 weeks at which times histology tissue scores, mucosal cytokine production, and viral assessments were performed.

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