Line Plot from Scientific Research

The PPS stratified by the size of the matrix, with line colors corresponding to those of the text and matrices in panel B. The x-axis represents sequencing yield in the targeted area, under a conservative assumption of 50% quality control data loss. The logarithmic y-axis shows the raw estimated price of sequencing the samples from a single individual. The dots represent empirical data from single batched sequencing at the specified batch sizes, including the sensitivity for loss-of-function and/or known pathogenic (LoF/P) variant detection.

DOI