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Phylogenetic trees of somatic mutation evolution in multi-sector samples from d patient M14. The length of the branch is relative to the number of mutations. Dashed lines indicate a relatively larger number of mutations that cannot be scaled for visualization. Indicated alterations are GBM driver alterations and RNA expression of TMZ-resistant markers. amp, amplification; del, deletion; higher_exp, higher transcriptomic expression compared to other sample/samples. Blue, TMZ-sensitive; red, TMZ-resistant.

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