Overlap between GRNs and ChIP-seq regulatory networks. The control consisting of TF-target pairs was generated randomly using the same TF sets and target sets for each dataset. The random TF-target pairs were generated 1,000 times for each GRN in each dataset. The average value of the overlaps between random targets and ChIP-seq targets was compared to the overlaps between GRN predictions and ChIP-seq targets using the 2 test. In addition, because three types of GRN were constructed using the same TFs set and targets set in each dataset, the comparisons of overlapping targets among mmGRN, TTGRN, and TmGRN were also performed using the 2 test.
