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The measured and predicted changes in gene expression (expressed as an unsigned percentage) due to enhancer knockout as a function of the distance between the gene and the enhancer. Values < 0.1% and > 100% are truncated. Shown are only validated enhancer-gene pairs from Fulco et al. [ 21 ] and Gasperini et al. [ 20 ]. Enformer attributes significantly less effect to most validated enhancers than the experiments suggest. This phenomenon is particularly strong for distal enhancers
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