Summary of key features of m6A methylation in plants. Plant species with known m6A profiles on a global scale are shown in a phylogenetic tree (left). The key m6A features (right) are summarized based on the studies in Pyrus bretschneideri (pear) [116], Malus hupehensis (apple) [108], Fragaria vesca (strawberry) [117], Hippophae rhamnoides (sea-buckthorn) [118], Glycine max (soybean) [27], Populus trichocarpa (populus) [119, 120, 121], Brassica rapa (pak-choi) [122], Arabidopsis thaliana (Arabidopsis) [28, 29], Gossypium hirsutum (cotton) [133, 136], Solanum lycopersicum (tomato) [97, 123, 124], Triticum aestivum (common wheat) [125, 126], Aegilops tauschii (rough-spike hard grass) [27], Oryza sativa (rice) [92, 127], Sorghum bicolor (sorghum) [128], Zea mays (maize) [134], Physcomitrella patens (earthmoss) [27], and Chlamydomonas reinhardtii (green algae) [130]. Among these features, the correlation with gene expression is shown at the transcriptome-wide basis. R = A/G; W = A/U; K = G/U; Y = C/U; D = A/G/U; H = A/C/U; V = A/G/C.
