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m6A modifications are influenced by various endogenous and environmental signals as shown in the following studies: developmental stages (strawberry [117], wheat [125]); different organs (Arabidopsis [137]); ecotype divergence (Arabidopsis [138]); blue light (Arabidopsis [79]); salt stress (Arabidopsis [139, 140], sweet sorghum [128], rice [141], sugar beet [142], cotton [133]); heat/low temperature (pak-choi [122], Arabidopsis [143], tomato [124]); cadmium stress (rice [127], barley [132]); drought stress (sea-buckthorn [118], populus [119], apple [135, 144]); pathogen infection (apple [108], rice [145], wheat [126], watermelon [131], pear [116]); and nematode infection (soybean [146]).
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