Scatter Plot from Scientific Research

The relationship between C4A GREx and 145 phenotypes was tested in the multi-ancestry cohort ( N s per phenotype ~ 6000). Increased genetically regulated expression of C4A was associated with lower scores on the UPPS-P Impulsive Behavior Scale (Lynam, [ 27 ]) lack of premeditation/planning subscale (FDR-corrected P = 0.004). Phenotypes are grouped into broad categories by color. Negative or positive associations with C4A GREx are indicated by the direction of arrows. The FDR-based threshold for phenome-wide significance is indicated by the red dashed line.

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