Atomic model of GluN1-N2B di-eNMDAR. Middle panel shows the top-down views of NTD and LBD layers, with the COM distances between GluN1 and GluN2B NTDs or LBDs displayed. Right panel shows the comparison of the NTD tetrameric interface formed by two GluN2-R2 lobes between the GluN1-N2B di-eNMDAR and GluN1-N2A-N2B tri-eNMDAR, with the COM distance between two 5 helices or GluN2-R2 lobes indicated.