Protein Structure from Scientific Research

Atomic model of the GluN1-N2A-N2B tri-eNMDAR. GluN1(chain A), GluN2A, GluN1(chain C), and GluN2B subunits are colored in gray, orange, pistachio, and lavender, respectively. Right panel shows the top-down views of the NTD and LBD layers with the center-of-mass (COM) distances between each two NTDs or LBDs displayed. Cartoon diagrams illustrate the dimer-of-dimer formation within the NTD or LBD layers and the domain swapping feature between the two layers. In the LBD layer, the LBD intradimer and interdimer interfaces are marked with arrows.

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