Gel from Scientific Research

DNA crosslinking ability analysis by agarose gel electrophoresis of pBR322 plasmid DNA (0.2 ug/slot) treated with various formulations. Chlorambucil was used as the positive control (Chl). Lane 1, pBR322 without any treatment; lane 2, pBR322 + 120 umsodium dithionite (SDT); lanes 3-6, pBR322 with increasing concentration of Ru prodrug and 120 umSDT: lane 3, 5 umRu; lane 4, 10 umRu; lane 5, 15 umRu; lane 6, 20 umRu. Lane 7, pBR322 + 20 umref.

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