MC-38 tumor growth of untreated and PDOX-treated wild-type mice receiving CD8-depleting (yellow/green) and CD4-depleting (blue/purple) antibodies or mock. Data shown in (A)–(F) were collected from mice on day 20 post tumor challenge (PDOX treatment started on day 10). The p values in (A), (B), and (D)–(F) were calculated by unpaired Student’s t test and in (G) by ANOVA; *p < 0.05, **p < 0.01, ***p < 0.001. Data in (A), (B), (D), (E), and (G) are presented as mean ± SEM, and each dot in (A), (B), and (D) represents an individual mouse. Data shown are representative of 2 independent experiments. See alsoFigure S6.
