The cost per DALY averted for the base case reflects health-care use cost data in Pakistan, which represented the median cost of the ASPIRIN trial sites. Results are sorted by their effect on the cost per DALY averted with LDA treatment. The low and high LDA cost were based on the low ($00042 per day) and the high ($00393 per day) price per tablet in the 2015 International Medical Products Price Guide (inflated to 2020 US$ using the gross domestic product deflator for Pakistan). Low and high LDA effectiveness estimates were based on the upper and lower 95% CI values reported in the ASPIRIN trial.4For hospitalisation costs, the highest cost was in Pakistan ($9400), but we increased the high cost to $20000 to explore the effect of a higher than expected cost. Finally, we varied life expectancy across the range represented by the ASPIRIN trial sites (DR Congo had the shortest life expectancy [6235 years] and Guatemala had the longest [7202 years]). DALY=disability-adjusted life year. LDA=low-dose aspirin.