Bar Plot from Scientific Research

Quantification of the effect of knockdown of the 11 top candidate genes selected from the in vitro validated list on endogenous tau levels in the mouse brain. Blue dashed line indicates the 15% reduction of tau protein levels. In all bar graphs, each data point represents an individual animal. Total protein, vinculin (VCL), and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) serve as loading controls. Four independent biological repeats were performed for each knockdown. Data are represented as mean ± SEM.

DOI