Bar Plot from Scientific Research

Quantitation of the relative number of oligodendrocytes and astrocytes. The data were obtained from one newborn monkey targeted by control gRNA/Cas9 and two newborn monkeys targeted by CHD8 gRNA/Cas9. Brain sections (1.3 mm apart from each other) from the brain cortical region in the control gRNA/Cas9 (six sections) and CHD8 gRNA/Cas9 (eight sections) targeted monkeys were used for quantitative analysis. At least four images (×20) from each brain section were taken to obtain the average numbers of glial cells per mm 2 . The data are presented as means ± SEM ( n = 24 images for control gRNA/Cas9 and n = 32 images for CHD8 gRNA/Cas9). *** P < 0.001.

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