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The effects of IL-9 treatment and anti-IL-9 blockade in ZBTB18-sufficient and -deficient mice. Experimental design: Aicda+/CreERT2;Zbtb18fl/fl;Rosa26-Ai14 or Aicda+/CreERT2;Zbtb18+/+;Rosa26-Ai14 mice were immunized with NP-KLH and then given tamoxifen every other day, starting from day 4. An anti-IL-9 antibody or IL-9 or PBS was injected on days 8 and 10. The fractions of GC-derived MBCs were analyzed on day 12.
#Workflow#Flowchart#IL-9 Treatment#Anti-IL-9 Blockade#ZBTB18#Mice#Experimental Design#GC-Derived MBCs
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