Heatmap from Scientific Research

Gene expression clustering with RNA-seq data based on the 2,846 most variant genes on the left, right, pre-NAC and post-NAC samples of a cohort of six patients (20 samples) with RNA-seq data available. Cluster 1 is enriched in genes coding for early and late response to estrogens; cluster 2 is enriched in genes coding for TNF signaling, myogenesis and epithelialmesenchymal transition; cluster 3 is enriched in genes coding for G2M checkpoints, E2F targets and cellular cycle; and cluster 4 shows no clear enrichment in specific pathways.

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