Line Plot from Scientific Research

Accessibility dynamics of genes that gain (orange) and lose (blue) open peaks during differentiation from HSCs to erythroid cells. Trajectory was computed using Palantir, with each line representing a fit gene trend and circles at bottom depicting pseudotime values of each respective metacell. Middle: results of Gene Ontology analysis using immune cell gene signatures. Right: Opening peaks are enriched for GATA motifs, and closing peaks are enriched for PU.1, master regulators of erythroid and myeloid fates, respectively.

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