Density Plot from Scientific Research

Distance distributions obtained from a donor fluorescence decay analysis by a model-free MEM approach (Supplementary Note 15). The distance distribution from the NMR–SAXS ensemble 29 (light blue) was used as the prior distribution. The expected interdye distances for the compact apo and open holo states are shown as red and blue dashed lines (PDB 2YH0 and 2YH1). Shaded areas indicate the distance broadening due to the flexible dye linkers of 6 A. The distribution in the donor–acceptor distance R DA for different dye pairs is shown.

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