Domain organizations of the IFT-A components. IFT144, IFT140, IFT122 N , IFT122 C , IFT121, IFT139 and IFT43 are colored goldenrod, salmon, green, green yellow, turquoise, blue and violet, respectively. Black asterisks indicate the helices inserted between the second and third TPR repeats in IFT144, IFT140, IFT122, and IFT121. The head and base module components have light yellow and pale blue background colors, respectively. Models of IFT144 WD1 , IFT144 C , IFT140 C and IFT139 N built with the aid of AlphaFold-2 are shown in dashed ovals or circles. The middle disordered loop of IFT43 is shown in a dashed line.