Line Plot from Scientific Research

Schematic illustration showing chromatin-bound TF (green) recognized by its antibody (gray), which in turn recruits ProteinA-Tn5 (PrA-Tn5: dark blue) to tagment the accessible chromatin regions in the vicinity. The motif (red) bound by the TF is protected from tagmentation, leaving a footprint (FP) whose relative depth is calculated by dividing the absolute FP Depth by Flank Height (the height of peak signals immediately flanking the motif over the background). Created by S.M.

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