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Power of clinical variables and pre-treatment total serum N-glycans in predicting ORR. The grey line represents the performance obtained when ORR is predicted by a model including only clinical variables, i.e., age, sex, BMI, metastatic stage, dichotomized LDH levels, and ECOG performance-status. The green and magenta lines represent the performance resulting when the measured N-glycan (GP6) and derived traits (N-glycans containing antennary fucose and low-branched mono- and biantennary N-glycans) associated with ORR are included in the model, respectively.

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