Schematic diagram shows the site locations of PD-risk rare variants in a published cryoelectron microscopy (cryo-EM) structure of human SLC7A11 (PDB:7P9V). These variants were identified based on whole exome sequencing (WES) and whole genome sequencing (WGS) data from two local PD cohorts (local cohort) and several public PD cohorts (the access-granted UKB database, UKB cohort, and PD Variant Browser, PVB cohort).
