Volcano Plot from Scientific Research

Volcano plot following global phospho- (11,821 unique phospho-peptides detected) proteomic analysis of STLC-synchronized U2OSFAM83DGFP/GFPcells expressing FLAG-aGFP6M-PPP2CA compared with those expressing FLAG-aGFP6M-PPP2CAH118Q. Gray horizontal threshold indicates significance level of p = 0.05. Gray vertical threshold indicates 2-fold change. The top left quadrant indicates phospho-peptides that are hypo-phosphorylated in cells expressing FLAG-aGFP6M-PPP2CA over those expressing FLAG-aGFP6M-PPP2CAH118Q, colored red, whereas the top right quadrant indicates phospho-peptides that are hyper-phosphorylated in cells expressing FLAG-aGFP6M-PPP2CA over those expressing FLAG-aGFP6M-PPP2CAH118Q, colored blue. Phospho-peptide detected corresponding to FAM83D is labeled.

DOI