Top differentially expressed protein coding genes for each endothelial subcluster. The log fold change (shading) and p value (size) for each gene comparing ICM with NF within each endothelial subcluster is shown on the left. The relative expression in each endothelial subcluster separated by ICM and NF is shown on the right with the size of the dot representing the percent of nuclei expressing the gene and the shade representing the average log-normalized expression. Genes were selected as those expressed in at least 30% of nuclei from either the non-failing or ischemic cardiomyopathy groups with logFC > 1, FDR-adjusted p value < 0.05, and a low probability of being derived from background contamination. NF, non-failing; ICM, ischemic cardiomyopathy; EC, endothelial cell; logFC, log fold change comparing ICM with NF; Pct Expr, percent of nuclei expressing at non-zero levels; Avg logExpr, average log-normalized expression. See alsoTable S8.
