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Percent of R403Q alleles with indels in three untreated male or AAV9-Cas9 treated (low dose: n = 1 male, 2 females; medium dose, n = 3 females and high dose, n = 4 females) R403Q-129SvEv/S4 mice was assessed by next-generation sequencing of PCR-amplified LV gDNA and analyzed using CRISPResso2.
#Bar Plot#Error Bars#R403Q alleles#Indels#AAV9-Cas9#Next-generation sequencing#PCR#LV gDNA#CRISPResso2
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