Line Plot from Scientific Research

Longitudinal echocardiographic measurements (defined in Fig. 2 ) of the LVPW (left panel), LVPW/LVDd ratio (middle panel) and %FS (right panel) in WT 129SvEv/S4 ( n = 5 males, black line), untreated R403Q-129SvEv/S4 ( n = 6 males, red line) and R403Q-129SvEv/S4 mice treated with two doses of dual-AAV9 ABE8e ( n = 6 males, blue line). Untreated but not treated R403Q-129SvEv/S4 developed early-onset hypertrophy (increased LVPW thickness and increased LVPW/LVDd) and hypercontractility (increased FS).

DOI