Scatter Plot from Scientific Research

LoF variants in 32 genes were enriched in cases with POI when compared with controls (cases n = 1,030; controls n = 5,000). Genes with FDR < 0.3 are shown. The upper graph shows P values for difference in the prevalence of LoF variants between cases and control individuals generated by one-sided Fisher's exact tests; middle graph shows FDR; lower graph displays the allele frequency of LoF variants in each gene.

DOI