Box Plot from Scientific Research

Quantification of the percentage of spontaneous steatosis in PNPLA3 variant organoids. n = 11 independent replicates for PNPLA3 WT and PNPLA3 WT/I148M , n = 10 independent replicates for PNPLA3 I148M/I148M , n = 15 independent replicates for PNPLA3 KO from either two (WT, WT/I148M, I148M/I148M) or three (KO) clonal lines from two donors. Two-tailed nested t- test: KO versus WT and I148M/I148M versus WT, *** P < 0.0001; I148M/I148M versus WT/I148M, *** P = 0.0001. The box indicates the 25–75th percentiles, the center line indicates the median and the whiskers indicate minimum and maximum values.

DOI