GSEA of aFibRS in the GSE14333 subset of tumor samples collected before treatment comparing relapsing ( n = 13) to nonrelapsing ( n = 38) patients after CT. ES enrichment score, NES normalized enrichment score, FDR false discovery rate. TFS tumorfree survival, CRC colorectal cell line (HT29M6). Fib fibroblasts (CCD18Co), DFS diseasefree survival, HR hazard ratio, CI confidence interval, Ox oxaliplatin, GSEA gene set enrichment analysis, RLU relative luminescence unit. Twosided, unpaired t test p values ( p ) are indicated for b , e . Logrank (MantelCox test) p values ( p ) are indicated for a , c , d , f . GSEA nominal p value ( p ) and FDRadjusted p value are indicated for g , h . Source data are provided as a Source Data file.