Forest plot for subgroups of patients having BICR-assessed objective responses in FAS. *Other includes one patient with G719X and S768I mutations, and one patient with only L861Q mutation. The Cobas EGFR Mutation Test, Version 2, Roche Diagnostics, South Branchburg, NJ, USA, was used for EGFR mutations detection, which was not able to further confirm this patient’s specific G719X type. Abbreviation: FAS, full analysis set; CNS, central nervous system; ECOG, Eastern Cooperative Oncology Group; PS, performance status; BICR, blinded independent central review; ORR, objective response rate; DCR, disease control rate; CI, confidence interval; PR, partial response; SD, stable disease; PD, progressive disease
